Quantification of S100A12 (EN-RAGE) in Blood Varies with Sampling Method, Calcium and Heparin
نویسندگان
چکیده
منابع مشابه
Expression of S100A12 (EN-RAGE) in cystic fibrosis.
BACKGROUND Chronic airway inflammation and recurrent infections are a core phenomenon in cystic fibrosis (CF). Diagnosing acute infectious exacerbations is difficult in the presence of chronic inflammatory processes. S100A12 exhibits proinflammatory functions via interaction with the multiligand receptor for advanced glycation end products. Blocking this interaction inhibits inflammatory proces...
متن کاملAbsence of S100A12 in mouse: implications for RAGE-S100A12 interaction.
protein that binds to a repeated EP motif in the intracellular region of LAG-3, may participate in the down-regulation of the CD3/TCR activation pathway. Eur. J. Immunol. 31, 2885–2891 14 Huard, B. et al. (1995) CD4/major histocompatibility complex class II interaction analyzed with CD4and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins. Eur. J. Immunol. 25, 2718–2721 15 Barten, R. et a...
متن کاملSerum S100A12 (EN-RAGE) levels in patients with decreased renal function and subclinical chronic inflammatory disease.
BACKGROUND The calcium-binding protein S100A12 (EN-RAGE) causes inflammation through interaction with the multiligand receptor for advanced glycation end products (RAGE). The aim of the study was to determine S100A12 levels and describe their relationship to inflammatory markers in patients with decreased renal function. METHODS The studied group consisted of 46 patients with various degrees ...
متن کاملIncreased plasma S100A12 (EN-RAGE) levels in patients with type 2 diabetes.
S100A12, also called EN-RAGE (extracellular newly identified receptor for advanced glycation end products binding protein) or calcium-binding protein in amniotic fluid-1, is a ligand for RAGE. It has been shown that S100A12 induces adhesion molecules such as vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 in the vascular endothelial cell and mediates migration and activa...
متن کاملExpression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis.
OBJECTIVES Infiltration of synovial tissue by neutrophils is crucial in rheumatoid arthritis (RA), psoriatic arthritis (PsA) and seronegative arthritis (SA). Altered vascular function and endothelial activation are important in PsA. S100A12 (EN-RAGE) is secreted by activated granulocytes and binds to the receptor for advanced glycation end products, which induces nuclear factor (NF)-kappaB-depe...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2007
ISSN: 0300-9475,1365-3083
DOI: 10.1111/j.1365-3083.2006.01875.x